Topical cyclosporine A for mustard gas induced ocular surface disorders
نویسندگان
چکیده
منابع مشابه
Topical Cyclosporine A for Mustard Gas Induced Ocular Surface Disorders
PURPOSE To evaluate the effectiveness of topical cyclosporine A 0.05% for treatment of mustard gas-induced ocular surface disorders with special attention to conjunctival goblet cell density in patients with severe dry eye. METHODS This prospective clinical study included 20 eyes of 20 patients previously exposed to mustard gas with dry eye syndrome unresponsive to artificial tears. Before an...
متن کاملMustard Gas Induced Ocular Surface Disorders
Sulfur mustard is a vesicant agent with severe irritating effects on living tissues, including skin, mucous membranes, eyes, and the respiratory tract. The eyes are the most susceptible tissue to mustard gas effects, and varying degrees of ocular involvement are seen in 75% to 90% of exposed individuals. Most cases resolve uneventfully; however, a minority of exposed patients will have a contin...
متن کاملMustard Gas Induced Ocular Injuries
1 Mustard gas is a lipophilic, highly cytotoxic agent that rapidly penetrates tissue, and the eye is one of the organs mostly affected,[1] but skin, respiratory, gastrointestinal, and renal systems as well as the bone marrow may also be affected.[2] Mustard gas related ocular injuries can be divided into immediate, chronic, and delayed‐onset phases. Acute manifestations of varying degrees, incl...
متن کاملTopical Cyclosporine A for Treatment of Dry Eye Due to Chronic Mustard Gas Injury
PURPOSE To evaluate the efficacy of topical cyclosporine A (tCsA) for treatment of dry eye disease in patients suffering from chronic ocular complications of mustard gas (MG) injury. METHODS This interventional case series included patients with MG injury suffering from severe dry eye despite receiving artificial tears and punctal plugs. Patients were administered tCsA 0.05% twice daily for 3...
متن کاملTopical ciclosporin in the treatment of ocular surface disorders.
Mounting evidence suggests that inflammation is the key factor in the pathogenesis of various ocular surface diseases, with a complex interplay of genetic, environmental, and psychosocial factors. Management of these conditions is often challenging. Topical corticosteroids, with their associated side effects, are the mainstay of current treatments for patients with vision threatening disease. C...
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ژورنال
عنوان ژورنال: Journal of Ophthalmic and Vision Research
سال: 2015
ISSN: 2008-322X
DOI: 10.4103/2008-322x.156089